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Gene Expression Data
Assay Details
Assay
Reference: J:92174 Aberg T, et al., Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis. Dev Biol. 2004 Jun 1;270(1):76-93
Assay type: RNA in situ
MGI Accession ID: MGI:3055933
Gene symbol: Tgfb1
Gene name: transforming growth factor, beta 1
Probe: Tgfb1 probe4
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen E13 WT: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tooth Present Regionally restricted 2J Expression is at the tip of the tooth bud.
TS21: tooth mesenchyme Weak 2J

Specimen E14 WT: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cervical loop Strong 2K Expression is in the cervical loops.
TS22: tooth mesenchyme Strong 2K

Specimen E14 Runx2-/-: embryonic day 14.5; Runx2tm1Mjo/Runx2tm1Mjo (more )
Structure Level Pattern Image Note
TS22: cervical loop Absent 2L Absence of expression reflects a failure of cervical loop formation.
TS22: tooth mesenchyme Present 2L Expression in this mutant is the same as in wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory