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Gene Expression Data
Assay Details
Assay
Reference: J:88280 Romand R, et al., Complementary expression patterns of retinoid acid-synthesizing and -metabolizing enzymes in pre-natal mouse inner ear structures. Gene Expr Patterns. 2004 Mar;4(2):123-33
Assay type: RNA in situ
MGI Accession ID: MGI:3037144
Gene symbol: Aldh1a3
Gene name: aldehyde dehydrogenase family 1, subfamily A3
Probe: Raldh3 cDNA
Probe preparation: Antisense RNA
Assay notes: The probe length was reduced to approximately 150 nucleotides by alkaline hydrolysis.
Results
Specimen 1C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lateral semicircular canal Present Regionally restricted 1C Expression is in the baso-lateral region of the crista.
TS26: endolymphatic duct Present 1C
TS26: saccule Present Regionally restricted 1C Expression is in the lateral regions of the utrical and saccular maculae.
TS26: utricle Present Regionally restricted 1C Expression is in the lateral regions of the utrical and saccular maculae.

Specimen Not Shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: endolymphatic duct Present Regionally restricted Expression is strong in the duct up to the lower third of the endolymphatic sac and is absent in the remaining two thirds.

Specimen 3C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cochlear ganglion Present 3C
TS26: vestibulocochlear nerve cochlear component Weak 3C

Specimen 5A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lateral semicircular canal Present Regionally restricted 5A Expression is in the transitional epithelium extending towards the sensory region at the level of the crista ampullaris.
TS26: posterior semicircular canal Present Regionally restricted 5A Expression is in the transitional epithelium extending towards the sensory region at the level of the crista ampullaris.
TS26: superior semicircular canal Present Regionally restricted 5A Expression is in the transitional epithelium extending towards the sensory region at the level of the crista ampullaris.

Specimen 5B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: utricle epithelium Present 5B Expression is in the utricular sensory epithelia.

Specimen 5C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: saccule Present Regionally restricted 5C Expression is in the lateral regions of the saccular maculae.
TS26: vestibulocochlear nerve cochlear component Present 5C

Specimen 5D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cochlear ganglion Present 5D

Specimen Table 1: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lateral semicircular canal Present Regionally restricted Expression is absent in the crista sensory region.
TS26: endolymphatic duct Present
TS26: crus commune Absent
TS26: saccule Present
TS26: utricle Present
TS26: cochlear duct Present Regionally restricted Expression is absent in the Claudius/Hensen cell region and present in the stria vascularis.
TS26: organ of Corti Absent Including Kolliker's organ.
TS26: inner ear Present Regionally restricted Expression is regionally restricted in parts of the inner ear but is absent in the basilar membrane and in the Reissner's membrane.
TS26: cochlear ganglion Present
TS26: vestibulocochlear nerve cochlear component Present
TS26: otic cartilage Absent
TS26: vestibular ganglion Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory