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Gene Expression Data
Assay Details
Assay
Reference: J:83255 Chi CL, et al., The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum. Development. 2003 Jun;130(12):2633-44
Assay type: RNA in situ
MGI Accession ID: MGI:2677302
Gene symbol: Gbx2
Gene name: gastrulation brain homeobox 2
Probe: Gbx2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5C: embryonic day 8.0 (more )
Note: 7 somites. Littermate control; exact genotype not specified.
Structure Level Pattern Image Note
TS12: future hindbrain Present Regionally restricted 5C Expression in a band at the rostral end of the metencephalon and in the posterior hindbrain.
Specimen 5D: embryonic day 8.0; Fgf8tm1.3Mrt/Fgf8tm1.4Mrt, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant. 7 somites.
Structure Level Pattern Image Note
TS12: future hindbrain Present Regionally restricted 5D Expression is present in the posterior hindbrain; it is not present in a band at the rostral end of the metencephalon, as in controls.
Specimen Not shown: embryonic day 9.0; Fgf8tm1.3Mrt/Fgf8tm1.4Mrt, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant. 12-15 somites.
Structure Level Pattern Image Note
TS14: future hindbrain Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory