Gene Expression Data
Assay Details
Assay
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Reference:
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J:79392
Bai CB, et al., Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway. Development. 2002 Oct;129(20):4753-61
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:2676442
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Gene symbol:
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Pax6
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Gene name:
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paired box 6
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Results
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Specimen
6D:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * Swiss Webster
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Mutant Allele(s):
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Ptch1tm1Mps/Ptch1tm1Mps
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS15: neural tube |
Present |
Regionally restricted |
6D
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Authors state ventral spinal cord markers expand dorsally compared with wild-type embryos at E10.5.
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Specimen
6H:
embryonic day 10.5
(more )
Specimen
6H:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
|
Sex:
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Not Specified
|
Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: neural tube |
Present |
Regionally restricted |
6H
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Expressed at highest levels in the intermediate spinal cord.
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Specimen
6L:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * Swiss Webster
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Mutant Allele(s):
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Gli2tm1Alj/Gli2tm1Alj Ptch1tm1Mps/Ptch1tm1Mps
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: neural tube |
Present |
Regionally restricted |
6L
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The expansion of expression is shifted more ventrally. Expression at highest levels in the dorsal half of the spinal cord.
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Specimen
7D:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * Swiss Webster
|
Mutant Allele(s):
|
Gli2tm1Alj/Gli2tm1Alj
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: neural tube |
Present |
Regionally restricted |
7D
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Expression domain is shifted ventrally.
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