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Gene Expression Data
Assay Details
Assay
Reference: J:79392 Bai CB, et al., Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway. Development. 2002 Oct;129(20):4753-61
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2676441
Gene symbol: Shh
Gene name: sonic hedgehog
Antibody: 5E1
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 6A: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 6A Authors state ventral spinal cord markers expand dorsally compared with wild-type embryos at E10.5.

Specimen 6E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube floor plate Present 6E

Specimen 6I: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS17: neural tube Absent 6I
TS17: notochord Present 6I

Specimen 7A: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: neural tube Absent 7A


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory