Gene Expression Data
Assay Details
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Assay
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Reference:
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J:83431
Morgan EA, et al., Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia. Development. 2003 Jul;130(14):3095-109
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2675824
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Gene symbol:
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Msx2
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Gene name:
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msh homeobox 2
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Results
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Specimen
3M:
embryonic day 11.5
(more  )
Specimen
3M:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 11.5
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Sex:
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Male
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: genital tubercle |
Present |
Regionally restricted |
3M
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Expression was strong in the mesenchyme adjacent to the distal urethral plate epithelium (UPE), the UPE and the sinus epithelium. Expression was present along the rostral-caudal axis of the genital tubercle.
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Specimen
3N:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc
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Age:
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embryonic day 11.5
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Sex:
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Male
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: genital tubercle |
Present |
Regionally restricted |
3N
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As in wild type, expression was strong in the mesenchyme adjacent to the distal urethral plate epithelium(UPE) and in the distal UPE. Normal expression was present in the rostral genital tubercle. Expression was absent from the proximal UPE in the mutant.
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Specimen
3O:
embryonic day 12.5
(more )
Specimen
3O:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 12.5
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Sex:
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Male
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: genital tubercle |
Present |
Regionally restricted |
3O
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Expression was detected in the glans mesenchyme and the urethral plate epithelium.
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Specimen
3P:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc
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Age:
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embryonic day 12.5
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Sex:
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Male
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: genital tubercle |
Present |
Regionally restricted |
3P
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As in wild type, expression was detected in the glans mesenchyme and the distal urethral plate epithelium (UPE). Expression was absent from the proximal UPE in the mutant.
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Analysis Tools
