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Gene Expression Data
Assay Details
Assay
Reference: J:83431 Morgan EA, et al., Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia. Development. 2003 Jul;130(14):3095-109
Assay type: RNA in situ
MGI Accession ID: MGI:2675824
Gene symbol: Msx2
Gene name: msh homeobox 2
Probe: Msx2 probe3
Probe preparation: Antisense RNA
Results
Specimen 3M: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: genital tubercle Present Regionally restricted 3M Expression was strong in the mesenchyme adjacent to the distal urethral plate epithelium (UPE), the UPE and the sinus epithelium. Expression was present along the rostral-caudal axis of the genital tubercle.

Specimen 3N: embryonic day 11.5; Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc (more )
Structure Level Pattern Image Note
TS19: genital tubercle Present Regionally restricted 3N As in wild type, expression was strong in the mesenchyme adjacent to the distal urethral plate epithelium(UPE) and in the distal UPE. Normal expression was present in the rostral genital tubercle. Expression was absent from the proximal UPE in the mutant.

Specimen 3O: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: genital tubercle Present Regionally restricted 3O Expression was detected in the glans mesenchyme and the urethral plate epithelium.

Specimen 3P: embryonic day 12.5; Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc (more )
Structure Level Pattern Image Note
TS20: genital tubercle Present Regionally restricted 3P As in wild type, expression was detected in the glans mesenchyme and the distal urethral plate epithelium (UPE). Expression was absent from the proximal UPE in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory