Gene Expression Data
Assay Details
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Assay
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Reference:
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J:83431
Morgan EA, et al., Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia. Development. 2003 Jul;130(14):3095-109
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2675820
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Gene symbol:
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Nog
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Gene name:
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noggin
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Probe:
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Nog probe1
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Probe preparation:
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Antisense RNA
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Results
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Specimen
3E:
embryonic day 11.5
(more  )
Specimen
3E:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 11.5
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Sex:
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Male
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: genital tubercle |
Present |
Regionally restricted |
3E
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Expression was present in the lateral shelf mesenchyme but absent from the urethral plate epithelium and the adjacent mesenchyme.
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Specimen
3F:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc
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Age:
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embryonic day 11.5
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Sex:
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Male
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: genital tubercle |
Present |
Regionally restricted |
3F
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Expression was present ectopically in the mesenchyme flanking the proximal urethral plate epithelium.
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Specimen
3G:
embryonic day 12.5
(more )
Specimen
3G:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 12.5
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Sex:
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Male
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: genital tubercle |
Present |
Regionally restricted |
3G
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Expression was present in the lateral shelf mesenchyme and in the mesenchyme flanking the distal urethral plate epithelium.
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Specimen
3H:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc
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Age:
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embryonic day 12.5
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Sex:
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Male
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: genital tubercle |
Present |
Regionally restricted |
3H
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Unlike wild type, expression was strong in the mesenchyme flanking the medial and proximal urethral plate epithelium (UPE) and weak in the mesenchyme flanking the distal UPE. Expression was detected in a narrow band in the genital tubercle mesenchyme.
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Analysis Tools
