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Gene Expression Data
Assay Details
Assay
Reference: J:25096 Macleod KF, et al., p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev. 1995 Apr 15;9(8):935-44
Assay type: Northern blot
MGI Accession ID: MGI:2673892
Gene symbol: Cdkn1a
Gene name: cyclin dependent kinase inhibitor 1A
Probe: p21 probe5
Probe preparation: Double stranded DNA
Visualized with: Phosphorimaging
Results Image: 1A
 Sample Information Bands Other Sample Information
Lane AgeStructure 2.2 kb Amount Genetic BackgroundMutant Allele(s)Sex
Heart, wt P adult TS28: heart Trace 30 µg; total RNA Not Specified Not Specified
Heart, mut P adult TS28: heart Trace 30 µg; total RNA involves: 129S2/SvPas Trp53tm1Tyj/Trp53tm1TyjNot Specified
Thymus, wt P adult TS28: thymus Present 30 µg; total RNA Not Specified Not Specified
Thymus, mut P adult TS28: thymus Present (a) 30 µg; total RNA involves: 129S2/SvPas Trp53tm1Tyj/Trp53tm1TyjNot Specified
Lungs, wt P adult TS28: lung Present 30 µg; total RNA Not Specified Not Specified
Lungs, mut P adult TS28: lung Present (a) 30 µg; total RNA involves: 129S2/SvPas Trp53tm1Tyj/Trp53tm1TyjNot Specified
Muscle, wt P adult TS28: skeletal muscle Trace 30 µg; total RNA Not Specified Not Specified
Muscle, mut P adult TS28: skeletal muscle Trace 30 µg; total RNA involves: 129S2/SvPas Trp53tm1Tyj/Trp53tm1TyjNot Specified
Spleen, wt P adult TS28: spleen Present 30 µg; total RNA Not Specified Not Specified
Spleen, mut P adult TS28: spleen Absent (b) 30 µg; total RNA involves: 129S2/SvPas Trp53tm1Tyj/Trp53tm1TyjNot Specified
Testes, wt P adult TS28: testis Present 30 µg; total RNA Not Specified Male
Testes, mut P adult TS28: testis Present 30 µg; total RNA involves: 129S2/SvPas Trp53tm1Tyj/Trp53tm1TyjMale
Kidney, wt P adult TS28: metanephros Trace 30 µg; total RNA Not Specified Not Specified
Kidney, mut P adult TS28: metanephros Trace 30 µg; total RNA involves: 129S2/SvPas Trp53tm1Tyj/Trp53tm1TyjNot Specified
Intestine, wt P adult TS28: intestine Very strong 30 µg; total RNA Not Specified Not Specified
Intestine, mut P adult TS28: intestine Very strong 30 µg; total RNA involves: 129S2/SvPas Trp53tm1Tyj/Trp53tm1TyjNot Specified
Liver, wt P adult TS28: liver Trace 30 µg; total RNA Not Specified Not Specified
Liver, mut P adult TS28: liver Trace 30 µg; total RNA involves: 129S2/SvPas Trp53tm1Tyj/Trp53tm1TyjNot Specified
Brain, wt P adult TS28: brain Present 30 µg; total RNA Not Specified Not Specified
Brain, mut P adult TS28: brain Present 30 µg; total RNA involves: 129S2/SvPas Trp53tm1Tyj/Trp53tm1TyjNot Specified
Notes:
(a) Authors report slightly reduced expression in mutant compared with wild type.
(b) Authors report that expression was dependent on p53.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory