Ccnd1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:73071 Long F, et al., Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development. 2001 Dec;128(24):5099-108
Assay type:	RNA in situ
MGI Accession ID:	MGI:2178840
Gene symbol:	Ccnd1
Gene name:	cyclin D1

Probe:	cyclin D1 probe
Probe preparation:	Antisense labelled with S35 RNA

Results

6D WT ©

Specimen 6D WT: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: tibia cartilage condensation	Present		6D WT	Expression was present in the chondrocytes.

Specimen 6D Cre10;Smo^n/c: embryonic day 14.5; Smo^tm1Amc/Smo^tm2Amc, Tg(Col2a1-cre)10Amc/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: tibia cartilage condensation	Weak	Regionally restricted	6D Cre10;Smo^n/c	Expression was markedly downregulated in the chondrocytes compared to wild type.

6D Ihh^n/n ©

Specimen 6D Ihh^n/n: embryonic day 14.5; Ihh^tm1Amc/Ihh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS22: tibia cartilage condensation	Present		6D Ihh^n/n	Expression was markedly downregulated in the chondrocytes compared to wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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