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Gene Expression Data
Assay Details
Assay
Reference: J:75954 Dunwoodie SL, et al., Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm. Development. 2002 Apr;129(7):1795-806
Assay type: RNA in situ
MGI Accession ID: MGI:2178639
Gene symbol: Hes1
Gene name: hes family bHLH transcription factor 1
Probe: Hes1 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7G: embryonic day 10.5; Dll3tm1Rbe/Dll3+ (more )
Note: Genotype of specimen shown not specified; many be wild type or +/-. Authors state that the tail regions in 7G-I are arranged in a hypothetical progression, according to the oscillatory expression of Hes1.
Structure Level Pattern Image Note
TS17: tail somite Present Regionally restricted 7G Expression in the caudal-most somite; rostral expression is evident alone or in combination with a caudal expression domain.
TS17: tail unsegmented mesenchyme Present Regionally restricted 7G Three distinct patterns of expression were seen in +/+ and +/- embryos; broad caudal domain that appears to narrow rostrally to form a tight band coincident with somite formation.
Specimen 7H: embryonic day 10.5; Dll3tm1Rbe/Dll3+ (more )
Note: Genotype of specimen shown not specified; many be wild type or +/-. Authors state that the tail regions in 7G-I are arranged in a hypothetical progression, according to the oscillatory expression of Hes1.
Structure Level Pattern Image Note
TS17: tail somite Present Regionally restricted 7H Expression in the caudal-most somite; rostral expression is evident alone or in combination with a caudal expression domain.
TS17: tail unsegmented mesenchyme Present Regionally restricted 7H Three distinct patterns of expression were seen in +/+ and +/- embryos; broad caudal domain that appears to narrow rostrally to form a tight band coincident with somite formation.
Specimen 7I: embryonic day 10.5; Dll3tm1Rbe/Dll3+ (more )
Note: Genotype of specimen shown not specified; many be wild type or +/-. Authors state that the tail regions in 7G-I are arranged in a hypothetical progression, according to the oscillatory expression of Hes1.
Structure Level Pattern Image Note
TS17: tail somite Present Regionally restricted 7I Expression in the caudal-most somite; rostral expression is evident alone or in combination with a caudal expression domain.
TS17: tail unsegmented mesenchyme Present Regionally restricted 7I Three distinct patterns of expression were seen in +/+ and +/- embryos; broad caudal domain that appears to narrow rostrally to form a tight band coincident with somite formation.
Specimen 7J: embryonic day 10.5; Dll3tm1Rbe/Dll3tm1Rbe (more )
Structure Level Pattern Image Note
TS17: tail somite Absent 7J
TS17: tail unsegmented mesenchyme Present Regionally restricted 7J Authors report only a single, relatively narrow band of expression is detected, located rostrally.
Specimen 7K: embryonic day 10.5; Dll3tm1Rbe/Dll3tm1Rbe (more )
Structure Level Pattern Image Note
TS17: tail somite Absent 7K
TS17: tail unsegmented mesenchyme Present Regionally restricted 7K Authors report only a single, relatively narrow band of expression is detected, located rostrally.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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