Gene Expression Data
Assay Details
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Assay
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Reference:
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J:75954
Dunwoodie SL, et al., Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm. Development. 2002 Apr;129(7):1795-806
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2178638
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Gene symbol:
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Hes5
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Gene name:
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hes family bHLH transcription factor 5
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Probe:
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Hes5 probe 4
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
7A:
embryonic day 10.5; Dll3tm1Rbe/Dll3 +
(more  )
Note: Genotype of specimen shown not specified; many be wild type or +/-. Authors state that the tail regions in 7A-D are arranged in a hypothetical progression, according to the oscillatory expression of Hes1.
Specimen
7A:
(close  )
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Genetic Background:
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involves: 129P2/Ola * C57BL/6
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Mutant Allele(s):
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Dll3tm1Rbe/Dll3+
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Bouin's Fixative
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Note:
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Genotype of specimen shown not specified; many be wild type or +/-. Authors state that the tail regions in 7A-D are arranged in a hypothetical progression, according to the oscillatory expression of Hes1.
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Specimen
7B:
embryonic day 10.5; Dll3tm1Rbe/Dll3 +
(more )
Note: Genotype of specimen shown not specified; many be wild type or +/-. Authors state that the tail regions in 7A-D are arranged in a hypothetical progression, according to the oscillatory expression of Hes1.
Specimen
7B:
(close )
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Genetic Background:
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involves: 129P2/Ola * C57BL/6
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Mutant Allele(s):
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Dll3tm1Rbe/Dll3+
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Bouin's Fixative
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Note:
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Genotype of specimen shown not specified; many be wild type or +/-. Authors state that the tail regions in 7A-D are arranged in a hypothetical progression, according to the oscillatory expression of Hes1.
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Specimen
7C:
embryonic day 10.5; Dll3tm1Rbe/Dll3 +
(more )
Note: Genotype of specimen shown not specified; many be wild type or +/-. Authors state that the tail regions in 7A-D are arranged in a hypothetical progression, according to the oscillatory expression of Hes1.
Specimen
7C:
(close )
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Genetic Background:
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involves: 129P2/Ola * C57BL/6
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Mutant Allele(s):
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Dll3tm1Rbe/Dll3+
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Bouin's Fixative
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Note:
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Genotype of specimen shown not specified; many be wild type or +/-. Authors state that the tail regions in 7A-D are arranged in a hypothetical progression, according to the oscillatory expression of Hes1.
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Specimen
7D:
embryonic day 10.5; Dll3tm1Rbe/Dll3 +
(more )
Note: Genotype of specimen shown not specified; many be wild type or +/-. Authors state that the tail regions in 7A-D are arranged in a hypothetical progression, according to the oscillatory expression of Hes1.
Specimen
7D:
(close )
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Genetic Background:
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involves: 129P2/Ola * C57BL/6
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Mutant Allele(s):
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Dll3tm1Rbe/Dll3+
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Bouin's Fixative
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Note:
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Genotype of specimen shown not specified; many be wild type or +/-. Authors state that the tail regions in 7A-D are arranged in a hypothetical progression, according to the oscillatory expression of Hes1.
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Specimen
7E:
(close )
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Genetic Background:
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involves: 129P2/Ola * C57BL/6
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Mutant Allele(s):
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Dll3tm1Rbe/Dll3tm1Rbe
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Bouin's Fixative
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Specimen
7F:
(close )
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Genetic Background:
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involves: 129P2/Ola * C57BL/6
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Mutant Allele(s):
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Dll3tm1Rbe/Dll3tm1Rbe
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Bouin's Fixative
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Specimen
not shown:
(close )
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Genetic Background:
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involves: 129P2/Ola * C57BL/6
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Mutant Allele(s):
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Dll3tm1Rbe/Dll3tm1Rbe
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Bouin's Fixative
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: tail unsegmented mesenchyme |
Weak |
Regionally restricted |
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In one embryo, a single faint band was detected in rostral presomitic mesoderm
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Specimen
not shown:
(close )
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Genetic Background:
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involves: 129P2/Ola * C57BL/6
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Mutant Allele(s):
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Dll3tm1Rbe/Dll3tm1Rbe
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Bouin's Fixative
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