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Gene Expression Data
Assay Details
Assay
Reference: J:73282 Watari N, et al., Hoxa3 regulates integration of glossopharyngeal nerve precursor cells. Dev Biol. 2001 Dec 1;240(1):15-31
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2156488
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament clone 2H3
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2A,D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: glossopharyngeal nerve Present Uniform 2D , 2A
TS19: vagal nerve trunk Present Uniform 2D , 2A
Specimen 2B,E: embryonic day 11.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Note: Type 1 mutant.
Structure Level Pattern Image Note
TS19: vagal nerve trunk Present Uniform 2E , 2B
TS19: glossopharyngeal nerve Present Uniform 2E , 2B The nerve fibers between the two ganglia are missing.
Specimen 2C,F: embryonic day 11.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Note: Type 2 mutant.
Structure Level Pattern Image Note
TS19: vagal nerve trunk Present Uniform 2C , 2F
TS19: glossopharyngeal nerve Present Uniform 2F , 2C The IXth and Xth nerves are fused to form an abnormal bundle.
Specimen 4A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: central nervous system ganglion Present Uniform 4A
Specimen 4B: embryonic day 10.0; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS16: central nervous system ganglion Present Uniform 4B Staining in this mutant is the same as in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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