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Gene Expression Data
Assay Details
Assay
Reference: J:62024 Cau E, et al., Hes genes regulate sequential stages of neurogenesis in the olfactory epithelium. Development. 2000 Jun;127(11):2323-32
Assay type: RNA in situ
MGI Accession ID: MGI:2150005
Gene symbol: Ascl1
Gene name: achaete-scute family bHLH transcription factor 1
Probe: clone 1
Probe preparation: Antisense RNA
Results
Specimen 1C +/+: embryonic day 10.5 (more )
Note: This specimen was flat mounted for microscopic observation. Double labeled: brown - Ascl1; blue - Hes1 (assay MGI:2149996).
Structure Level Pattern Image Note
TS17: nasal pit Present Regionally restricted 1C Expression is restricted to the neuronal precurors, which are in the center of the structure.
Specimen 1F +/+: embryonic day 10.5 (more )
Note: This specimen was flat mounted for microscopic observation. Double labeled: blue - Ascl1; brown - Hes5 (assay MGI:2150001).
Structure Level Pattern Image Note
TS17: nasal pit Present Regionally restricted 1F Expression is restricted to the neuronal precurors, which are in the center of the structure.
Specimen Not shown Hes5-/-: embryonic day 10.5; Hes5tm1Fgu/Hes5tm1Fgu (more )
Note: This specimen was flat mounted for microscopic observation.
Structure Level Pattern Image Note
TS17: nasal pit Present Regionally restricted Expression is restricted to the neuronal precurors, which are in the center of the structure. Their number and distribution is the same as wild-type.
Specimen 2A +/+: embryonic day 10.5 (more )
Note: This specimen was flat mounted for microscopic observation.
Structure Level Pattern Image Note
TS17: nasal pit Present Graded 2A Expressing cells are located in the medial side and, to a lesser extent, in the lateral side of the structure.
Specimen 2B Hes1-/-: embryonic day 10.5; Hes1tm1Fgu/Hes1tm1Fgu (more )
Note: This specimen was flat mounted for microscopic observation.
Structure Level Pattern Image Note
TS17: nasal pit Present Uniform 2B The number of expressing cells is increased. Ectopically expressing cells are found ventrally and dorsally in the structure. There is a marked increase in the cells on the lateral side and in the medial domain, plus scattered cells in the center.
Specimen Not shown Hes1-/-;Hes5-/-: embryonic day 10.5; Hes1tm1Fgu/Hes1tm1Fgu, Hes5tm1Fgu/Hes5tm1Fgu (more )
Note: This specimen was flat mounted for microscopic observation.
Structure Level Pattern Image Note
TS17: nasal pit Present Uniform The number of expressing cells is increased. Ectopically expressing cells are found ventrally and dorsally in the structure. There is a marked increase in the cells on the lateral side and in the medial domain, plus scattered cells in the center.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory