About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:62024 Cau E, et al., Hes genes regulate sequential stages of neurogenesis in the olfactory epithelium. Development. 2000 Jun;127(11):2323-32
Assay type: RNA in situ
MGI Accession ID: MGI:2150005
Gene symbol: Ascl1
Gene name: achaete-scute family bHLH transcription factor 1
Probe: clone 1
Probe preparation: Antisense RNA
Results
Specimen 1C +/+: embryonic day 10.5 (more )
Note: This specimen was flat mounted for microscopic observation. Double labeled: brown - Ascl1; blue - Hes1 (assay MGI:2149996).
Structure Level Pattern Image Note
TS17: nasal pit Present Regionally restricted 1C Expression is restricted to the neuronal precurors, which are in the center of the structure.
Specimen 1F +/+: embryonic day 10.5 (more )
Note: This specimen was flat mounted for microscopic observation. Double labeled: blue - Ascl1; brown - Hes5 (assay MGI:2150001).
Structure Level Pattern Image Note
TS17: nasal pit Present Regionally restricted 1F Expression is restricted to the neuronal precurors, which are in the center of the structure.
Specimen Not shown Hes5-/-: embryonic day 10.5; Hes5tm1Fgu/Hes5tm1Fgu (more )
Note: This specimen was flat mounted for microscopic observation.
Structure Level Pattern Image Note
TS17: nasal pit Present Regionally restricted Expression is restricted to the neuronal precurors, which are in the center of the structure. Their number and distribution is the same as wild-type.
Specimen 2A +/+: embryonic day 10.5 (more )
Note: This specimen was flat mounted for microscopic observation.
Structure Level Pattern Image Note
TS17: nasal pit Present Graded 2A Expressing cells are located in the medial side and, to a lesser extent, in the lateral side of the structure.
Specimen 2B Hes1-/-: embryonic day 10.5; Hes1tm1Fgu/Hes1tm1Fgu (more )
Note: This specimen was flat mounted for microscopic observation.
Structure Level Pattern Image Note
TS17: nasal pit Present Uniform 2B The number of expressing cells is increased. Ectopically expressing cells are found ventrally and dorsally in the structure. There is a marked increase in the cells on the lateral side and in the medial domain, plus scattered cells in the center.
Specimen Not shown Hes1-/-;Hes5-/-: embryonic day 10.5; Hes1tm1Fgu/Hes1tm1Fgu, Hes5tm1Fgu/Hes5tm1Fgu (more )
Note: This specimen was flat mounted for microscopic observation.
Structure Level Pattern Image Note
TS17: nasal pit Present Uniform The number of expressing cells is increased. Ectopically expressing cells are found ventrally and dorsally in the structure. There is a marked increase in the cells on the lateral side and in the medial domain, plus scattered cells in the center.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory