Hes5 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:62024 Cau E, et al., Hes genes regulate sequential stages of neurogenesis in the olfactory epithelium. Development. 2000 Jun;127(11):2323-32
Assay type:	RNA in situ
MGI Accession ID:	MGI:2150001
Gene symbol:	Hes5
Gene name:	hes family bHLH transcription factor 5

Probe:	Hes5 cDNA5
Probe preparation:	Antisense RNA

Results

1D ©

Specimen 1D +/+: embryonic day 10.5 (more

)
Note: This specimen was flat mounted for microscopic observation.

Structure	Level	Pattern	Image	Note
TS17: olfactory placode	Present	Clusters	1D	Expression is present in cell clusters, located both apically and basally, in the olfactory placode and olfactory epithelium.

1E ©

Specimen 1E Mash1-/-: embryonic day 10.5; Ascl1^tm1And/Ascl1^tm1And (more

)
Note: This specimen was flat mounted for microscopic observation.

Structure	Level	Pattern	Image	Note
TS17: nasal pit	Present	Regionally restricted	1E	Expression is restricted to a small domain in the olfactory placode where neurogenesis is not affected by the mutation.

1F ©

Specimen 1F +/+: embryonic day 10.5 (more

)
Note: This specimen was flat mounted for microscopic observation. Double labeled: brown - Hes5; blue - Ascl1 (assay MGI:2150005).

Structure	Level	Pattern	Image	Note
TS17: olfactory placode	Present	Clusters	1F	Expression is present in cell clusters, located both apically and basally, in the olfactory placode and olfactory epithelium. These clusters are intermingled with and more centrally located than the Ascl1+ cells.

1I ©

Specimen 1I +/+: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: olfactory epithelium	Present	Single cells	1I	Expression is present in scattered basal cells; there are no expressing cells located apically.

1J ©

Specimen 1J Mash1-/-: embryonic day 12.5; Ascl1^tm1And/Ascl1^tm1And (more

)

Structure	Level	Pattern	Image	Note
TS20: olfactory epithelium	Absent		1J

Specimen Not shown +/+: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: olfactory epithelium	Absent

2G ©

Specimen 2G +/+: embryonic day 10.5 (more

)
Note: This specimen was flat mounted for microscopic observation.

Structure	Level	Pattern	Image	Note
TS17: nasal pit	Present		2G

2H ©

Specimen 2H Hes1-/-: embryonic day 10.5; Hes1^tm1Fgu/Hes1^tm1Fgu (more

)
Note: This specimen was flat mounted for microscopic observation.

Structure	Level	Pattern	Image	Note
TS17: nasal pit	Present		2H	There is ectopic expression; it is upregulated compared to wild-type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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