Epha3 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:70745 Suda Y, et al., Emx2 directs the development of diencephalon in cooperation with Otx2. Development. 2001 Jul;128(13):2433-50
Assay type:	RNA in situ
MGI Accession ID:	MGI:2148279
Gene symbol:	Epha3
Gene name:	Eph receptor A3

Probe:	Mek4 probe
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

2O ©

Specimen 2O: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: midbrain	Strong	Graded	2O	High levels in anterior tectum; low levels caudally.

2P ©

Specimen 2P: embryonic day 11.5; Emx2^tm1Sia/Emx2^tm1Sia, Otx2^tm1Sia/Otx2⁺ (more

)
Note: Emx2 and Otx2 heterozygotes were maintained by crosses with CBA mice. Single Emx2 and Otx2 heterozygotes (from F3 and F5 generations, respectively) were mated to generate double heterozygotes, which were subsequently mated to generate the double mutants.

Structure	Level	Pattern	Image	Note
TS19: midbrain	Present	Graded	2P	Authors report normal patterns of expression in double mutants.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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