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Gene Expression Data
Assay Details
Assay
Reference: J:69851 Patterson LT, et al., Hoxa11 and Hoxd11 regulate branching morphogenesis of the ureteric bud in the developing kidney. Development. 2001 Jun;128(11):2153-61
Assay type: RNA in situ
MGI Accession ID: MGI:2137141
Gene symbol: Wnt11
Gene name: wingless-type MMTV integration site family, member 11
Probe: Wnt11 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6A: embryonic day 13.5; Hoxa11tm1Ssp/Hoxa11+, Hoxd11tm1Mrc/Hoxd11+ (more )
Structure Level Pattern Image Note
TS21: ureter Present Regionally restricted 6A Expression is in ureteric bud termini.
Specimen 6B,C: embryonic day 13.5; Hoxa11tm1Ssp/Hoxa11tm1Ssp, Hoxd11tm1Mrc/Hoxd11tm1Mrc (more )
Structure Level Pattern Image Note
TS21: ureter Present Regionally restricted 6B , 6C Expression is only present in the branch tips ot the uteric buds. In buds that failed to branch there is no expression.
Specimen 7A: embryonic day 13.5; Hoxa11tm1Ssp/Hoxa11tm1Ssp, Hoxd11tm1Mrc/Hoxd11tm1Mrc (more )
Structure Level Pattern Image Note
TS21: ureter Present Regionally restricted 7A Expression is in the organized epithelial structures of bud branches. This organization was often defective.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory