Gene Expression Data
Assay Details
Assay
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Reference:
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J:41878
Zoltewicz JS, et al., oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1. Development. 1999 Nov;126(22):5085-95
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1346418
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Gene symbol:
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Emx2
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Gene name:
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empty spiracles homeobox 2
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Probe:
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Emx2 probe3
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Probe preparation:
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RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
not shown:
embryonic day 9.5
(more )
Specimen
not shown:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS15: telencephalon |
Present |
Regionally restricted |
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Emx2 is expressed in the dorsal telencephalon.
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Specimen
not shown:
embryonic day 9.5; Pgap1oto/Pgap1 +
(more )
Note: moderate oto mutant
Specimen
not shown:
(close )
Genetic Background:
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involves: STOCK In(1)1Rk/J
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Mutant Allele(s):
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Pgap1oto/Pgap1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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moderate oto mutant
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Structure |
Level |
Pattern |
Image |
Note |
TS15: telencephalon |
Present |
Regionally restricted |
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Expression in this mutant is the same as in wild-type embryos.
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Specimen
6A:
embryonic day 8.5
(more )
Specimen
6A:
(close )
Genetic Background:
|
Not Specified
|
Age:
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embryonic day 8.5
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Sex:
|
Not Specified
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Type:
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whole mount
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Specimen
6B:
(close )
Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J * STOCK In(1)1Rk/J
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Mutant Allele(s):
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Lhx1tm1Bhr/Lhx1+ Pgap1oto/Pgap1+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: future prosencephalon |
Present |
Regionally restricted |
6B
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Reduced expression shows a reduction in the telencephalic region, with a right-sided bias identical to defects that are seen in oto homozygotes.
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