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Gene Expression Data
Assay Details
Assay
Reference: J:41878 Zoltewicz JS, et al., oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1. Development. 1999 Nov;126(22):5085-95
Assay type: RNA in situ
MGI Accession ID: MGI:1346415
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe10
Probe preparation: RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: telencephalon Strong Regionally restricted 3C Expression is present in the commissural plate.
TS15: future brain Moderate Regionally restricted 3C Expression is present in the commissural plate at the mid-hindbrain junction.
TS15: 1st branchial arch Present Regionally restricted 3C Expression is restricted to the anterior and proximal region of the arch.

Specimen 3D: embryonic day 9.5; Pgap1oto/Pgap1+ (more )
Structure Level Pattern Image Note
TS15: telencephalon Weak Regionally restricted 3D Expression is reduced in the commissural plate of oto embryos.
TS15: future brain Moderate Regionally restricted 3D Expression in this mutant is the same as in wild-type embryos.

Specimen not shown: embryonic day 9.5; Pgap1oto/Pgap1+ (more )
Note: mildly affected oto mutant
Structure Level Pattern Image Note
TS15: 1st branchial arch Present Regionally restricted Fgf8 is expressed in a continuous stripe across the anterior edge of the arch.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory