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Gene Expression Data
Assay Details
Assay
Reference: J:34184 Yang XM, et al., Expression of the met receptor tyrosine kinase in muscle progenitor cells in somites and limbs is absent in Splotch mice. Development. 1996 Jul;122(7):2163-71
Assay type: RNA in situ
MGI Accession ID: MGI:1338958
Gene symbol: Hgf
Gene name: hepatocyte growth factor
Probe: Hgf cDNA7
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: For the exact breeding scheme of mutant mice, see the original reference.
Results
Specimen 1F: embryonic day 9.75 (more )
Note: 36 somites.
Structure Level Pattern Image Note
TS15: embryo Present Uniform 1F
Specimen 1G: embryonic day 10.0 (more )
Note: 45 somites.
Structure Level Pattern Image Note
TS16: forelimb bud Present 1G
Specimen 1M: embryonic day 10.0 (more )
Note: 45 somites.
Structure Level Pattern Image Note
TS16: forelimb bud mesenchyme Present Regionally restricted 1M Expression is over the dorsal and ventral sides.
Specimen 1N: embryonic day 11.0 (more )
Note: 53 somites.
Structure Level Pattern Image Note
TS18: forelimb bud mesenchyme Present Regionally restricted 1N Expression is ventral in the distal half of the limb.
Specimen 1O: embryonic day 11.5 (more )
Note: 58 somites.
Structure Level Pattern Image Note
TS19: handplate mesenchyme Present Regionally restricted 1O There is no expression on the dorsal side, but there is expression on the ventral side.
Specimen 1P: embryonic day 11.5 (more )
Note: 58 somites.
Structure Level Pattern Image Note
TS19: handplate mesenchyme Present Regionally restricted 1P Expression colocalizes with Met expression on the ventral side.
Specimen 3A: embryonic day 10.5 (more )
Note: 46-50 somites.
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 3A Expression is in close proximity to Met-expressing cells.
Specimen 4J: embryonic day 11.0; Pax3Sp-2H/Pax3Sp-2H (more )
Note: 48 somites.
Structure Level Pattern Image Note
TS18: forelimb bud mesenchyme Present Regionally restricted 4J Expression in this mutant is the same as in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory