Gene Expression Data
Assay Details
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Assay
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Reference:
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J:46379
Wang W, et al., Inner ear and maternal reproductive defects in mice lacking the Hmx3 homeobox gene. Development. 1998 Feb;125(4):621-34
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1310070
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Gene symbol:
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Hmx3
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Gene name:
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H6 homeobox 3
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Probe:
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pW186
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Probe preparation:
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Antisense labelled with S35 RNA
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Assay notes:
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It is unclear whether the null embryos and mice are carrying the neo or the lacZ allele. The assays have been annotated using the lacZ allele (MGI:1857541) but MGI:1857577 could have been used instead.
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Results
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Specimen
6C:
embryonic day 14.5
(more  )
Specimen
6C:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: inner ear |
Present |
Regionally restricted |
6C
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Expression was observed in the semicircular ducts.
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| TS22: utricle |
Present |
Regionally restricted |
6C
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Expression was observed in the semicircular ducts.
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Specimen
6D:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Mutant Allele(s):
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Hmx3tm2Tlu/Hmx3tm2Tlu
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Age:
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embryonic day 14.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: inner ear |
Present |
Regionally restricted |
6D
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Expression was observed in the semicircular ducts.
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| TS22: utricle |
Present |
Regionally restricted |
6D
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Expression was observed in the semicircular ducts.
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Specimen
7 unpregnant +/+:
postnatal
(more )
Note: Unpregnant uterus.
Specimen
7 unpregnant +/+:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal
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Sex:
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Female
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Unpregnant uterus.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: uterus |
Present |
Regionally restricted |
7_Hmx3 unpregnant +/+
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Expression is in the uterine stroma, with highest expression in cells closest to the epithelial layer of the endometrium and expression showing a mediolateral decrease with increasing distance from the uterine lumen.
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Specimen
7 unpregnant -/-:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Mutant Allele(s):
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Hmx3tm2Tlu/Hmx3tm2Tlu
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Age:
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postnatal
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Sex:
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Female
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Unpregnant uterus.
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Specimen
7 pregnant +/+:
postnatal
(more )
Note: Pregnant uterus E4.5.
Specimen
7 pregnant +/+:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal
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Sex:
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Female
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Pregnant uterus E4.5.
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Specimen
7 pregnant -/-:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Mutant Allele(s):
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Hmx3tm2Tlu/Hmx3tm2Tlu
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Age:
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postnatal
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Sex:
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Female
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Pregnant uterus E4.5.
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Analysis Tools