Analysis Tools
behavior/neurological
 |
• less time spent in open arms in elevated plus maze test
|
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• less time spent in center in open field test
• normal total distance travelled
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• no preference for either novel or familiar object in novel object recognition test
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• no preference for novel mice over familiar mice in three-chamber test
• normal sociability
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growth/size/body
microcephaly
(
J:379200
)
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nervous system
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• thinner layers II-VI
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• thin neocortex at age P0
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• fewer basal progenitor cells in E12.5 embryo cortex
• normal number of apical progenitor cells in E12.5 embryo cortex
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| Renpenning syndrome | DOID:0060179 |
OMIM:309500 |
J:379200 | |
