Phenotypes for Tcf12 Tg(EIIa-cre)C5379Lmgd Twist1 MGI:8247991 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Tcf12^tm3Zhu/Tcf12⁺ Tg(EIIa-cre)C5379Lmgd/0 Twist1^tm1Bhr/Twist1⁺
Genetic Background	involves: 129 * 129S7/SvEvBrd * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcf12^tm3Zhu mutation (1 available); any Tcf12 mutation (75 available)
Tg(EIIa-cre)C5379Lmgd mutation (5 available)
Twist1^tm1Bhr mutation (4 available); any Twist1 mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

premature coronal suture closure ( J:198060 )

• mice show severe coronal synostosis

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
craniosynostosis		DOID:2340	OMIM:182212 OMIM:600593	J:198060

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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