Phenotypes Associated with This Genotype

Genotype
MGI:5825263

cx2

• Allelic Composition: Ddr2^{tm1b(EUCOMM)Wtsi}/Ddr2^{tm1b(EUCOMM)Wtsi}; Tg(MMTV-PyVT)634Mul/0
• Genetic Background: involves: C57BL/6N * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased mammary gland tumor incidence ( J:236031 )

• mice develop primary mammary gland tumors with a similar latency and burden as single Tg(MMTV-PyVT)634Mul/0 mice

decreased metastatic potential ( J:236031 )

• mice show a reduction in the number of macroscopic and microscopic metastases in the lungs compared to single Tg(MMTV-PyVT)634Mul/0 mice

integument

increased mammary gland tumor incidence ( J:236031 )

• mice develop primary mammary gland tumors with a similar latency and burden as single Tg(MMTV-PyVT)634Mul/0 mice

endocrine/exocrine glands

increased mammary gland tumor incidence ( J:236031 )

• mice develop primary mammary gland tumors with a similar latency and burden as single Tg(MMTV-PyVT)634Mul/0 mice