About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5572808
Allelic
Composition
Tshrhyt-3J/Tshrhyt-3J
Genetic
Background
CByJ;CXB10-Tshrhyt-3J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tshrhyt-3J mutation (1 available); any Tshr mutation (7 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands

growth/size/body
• homozygotes are approximately half the normal size

mortality/aging
• many homozygotes die around 3 weeks of age, and if they survive through wean age will usually survive to adulthood and live a relatively normal lifespan
• there is some premature death in the adult population
• heterozygous intercrosses produce fewer than the expected 25% homozygotes

reproductive system
• decreased fertility compared with wild-type controls
• Background Sensitivity: with increased BALB/cByJ in the background some male homozygotes will breed, but fertility is still decreased relative to wild-type littermates

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
congenital hypothyroidism DOID:0050328 OMIM:PS275200
J:210510


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
07/02/2024
MGI 6.13
The Jackson Laboratory