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Tshrhyt-3J
Spontaneous Allele Detail
Summary
Symbol: Tshrhyt-3J
Name: thyroid stimulating hormone receptor; hypothyroid 3 Jackson
MGI ID: MGI:5554389
Gene: Tshr  Location: Chr12:91367767-91507283 bp, + strand  Genetic Position: Chr12, 44.51 cM
Alliance: Tshrhyt-3J page
Mutation
origin
Strain of Origin:  CXB10/HiAJ-Cacna1asmrl/GrsrJ
Mutation
description
Allele Type:    Spontaneous (Not Specified)
Mutation:    Intragenic deletion
 
Mutation detailsThis spontaneous 233 bp intragenic deletion is predicted to result in a frameshift, which, if translated, would introduce 11 novel amino acids beginning at amino acid 442 prior to a premature stop codon. (J:222308)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tshr Mutation:  7 strains or lines available
References
Original:  J:210510 Harris BS, et al., A spontaneous mutation in thyroid stimulating hormone receptor that allows partial fertility in both females and males. MGI Direct Data Submission. 2014;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory