Phenotypes Associated with This Genotype

Genotype
MGI:5529108

• Allelic Composition: Mstn^Cmpt/Mstn⁺
• Genetic Background: either: HCI or HCR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

abnormal muscle morphology ( J:43299 )

increased skeletal muscle mass ( J:43299 )

• hypermuscularity is variable but always greater than found in wild-type mice

• phenotype is more distinct among males

• variable expression depends on presence/absence of at least one modifier

growth/size/body

abnormal body composition ( J:43299 )

increased body weight ( J:43299 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
myostatin-related muscle hypertrophy		DOID:0111072	OMIM:614160	J:43299