Phenotypes Associated with This Genotype

Genotype
MGI:5498329

• Allelic Composition: Dnm2^b2b2159Clo/Dnm2^b2b2159Clo
• Genetic Background: C57BL/6J-Dnm2^b2b2159Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 2159-003-2 (E16.5) shows parallel outflow tracts which is diagnosed as DORV by EFIC imaging

cardiovascular system

vascular ring ( J:175213 )

• retroesophageal subclavian forming vascular ring

aorta hypoplasia ( J:175213 )

double outlet right ventricle ( J:175213 )

overriding aortic valve ( J:175213 )

ventricular septal defect ( J:175213 )

• subaortic ventricular septal defect

perimembraneous ventricular septal defect ( J:175213 )

muscular ventricular septal defect ( J:175213 )

craniofacial

cleft palate ( J:175213 )

digestive/alimentary system

cleft palate ( J:175213 )

nervous system

hydrocephaly ( J:175213 )

encephalomeningocele ( J:175213 )

renal/urinary system

polycystic kidney ( J:175213 )

hydronephrosis ( J:175213 )

vision/eye

microphthalmia ( J:175213 )

growth/size/body

cleft palate ( J:175213 )

polycystic kidney ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cystic kidney disease		DOID:2975		J:175213