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Phenotypes Associated with This Genotype
Genotype
MGI:5469045
Allelic
Composition		 Srrm4bv/Srrm4bv
Tg(Myo7a-Srrm4)#Bban/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srrm4bv mutation (2 available); any Srrm4 mutation (38 available)
Tg(Myo7a-Srrm4)#Bban mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

The abnormal inner hair cell phenotype of Srrm4bv/Srrm4bv mice is rescued by hair-cell targeted expression of the Tg(Myo7a-Srrm4)#Bban transgene

behavior/neurological
behavior/neurological phenotype ( J:193641 )
N
• mice exhibit restored balance

hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:193641 )
N
• hearing, utricle and cochlear inner cells are restored

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory