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Phenotypes Associated with This Genotype
Genotype
MGI:5432799
cx16
Allelic
Composition		 Gli2tm3.1Blnw/Gli2tm3.1Blnw
Ptch1tm1Mps/?
Genetic
Background		 involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gli2tm3.1Blnw mutation (0 available); any Gli2 mutation (169 available)
Ptch1tm1Mps mutation (2 available); any Ptch1 mutation (113 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal neural tube morphology ( J:186503 )
• at E10.5, Patch1-lacZ expression is slightly increased and dorsally expanded in the neural tube compared to in wild-type mice

nervous system
abnormal neural tube morphology ( J:186503 )
• at E10.5, Patch1-lacZ expression is slightly increased and dorsally expanded in the neural tube compared to in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory