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Phenotypes Associated with This Genotype
Genotype
MGI:4365579
Allelic
Composition
Mmp3tm1Mrl/Mmp3tm1Mrl
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/10ScSn * RIII
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mmp3tm1Mrl mutation (0 available); any Mmp3 mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• DNFB-sensitized and challenged mice exhibit minimal proliferation of lymphocyte in draining lymph nodes unlike similarly treated wild-type mice
• however, lymphocyte proliferation in response to Con A is normal
• DNFB-sensitized and challenged mice exhibit reduced contact hypersensitivity driven ear swelling compared with similarly treated wild-type mice
• however, irritant initiated, chemically-induced inflammation to phenol is normal

hematopoietic system
• DNFB-sensitized and challenged mice exhibit minimal proliferation of lymphocyte in draining lymph nodes unlike similarly treated wild-type mice
• however, lymphocyte proliferation in response to Con A is normal


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/26/2026
MGI 6.24
The Jackson Laboratory