Phenotypes Associated with This Genotype

Genotype
MGI:4357787

• Allelic Composition: Terf1^tm1.1Blas/Terf1^tm1.1Blas; Tg(KRT5-cre)1Tak/0; Trp53^tm1Tyj/Trp53^tm1Tyj
• Genetic Background: involves: 129 * C3H * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:152077 )

N • perinatal and early postnatal lethality is normal

neoplasm

increased skin squamous cell carcinoma incidence ( J:152077 )

• in tail and ear skin of older mice

craniofacial

oral leukoplakia ( J:152077 )

digestive/alimentary system

oral leukoplakia ( J:152077 )

integument

integument phenotype ( J:152077 )

N • hair growth and skin pigmentation are normal

abnormal nail morphology ( J:152077 )

increased skin squamous cell carcinoma incidence ( J:152077 )

• in tail and ear skin of older mice

growth/size/body

oral leukoplakia ( J:152077 )