Phenotypes for Ppp1r15a Ppp1r15b MGI:3833925 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ppp1r15a^tm1Dron/Ppp1r15a^tm1Dron Ppp1r15b^tm1Dron/Ppp1r15b^tm1Dron
Genetic Background	involves: 129P2/OlaHsd * 129S6/SvEvTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp1r15a^tm1Dron mutation (0 available); any Ppp1r15a mutation (23 available)
Ppp1r15b^tm1Dron mutation (0 available); any Ppp1r15b mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Ppp1r15a^tm1Dron/Ppp1r15a^tm1Dron Ppp1r15b^tm1Dron/Ppp1r15b^tm1Dron embryos fail to develop past the preimplantation period

mortality/aging

embryonic lethality before implantation, complete penetrance ( J:144954 )

• embryos do not develop beyond pre-implantation stages

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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