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Phenotypes Associated with This Genotype
Genotype
MGI:3806462
hm2
Allelic
Composition
Pdgfrbtm1Sor/Pdgfrbtm1Sor
Genetic
Background
involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdgfrbtm1Sor mutation (1 available); any Pdgfrb mutation (89 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• perivascular cells are missing from angiogenic sprouts
• ES cells fail to respond to application of Pdgfb by forming a peripheral capillary plexus as wild-type cells do
• however, formation of Pdgf-independent vascular structures is normal


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory