Phenotypes Associated with This Genotype

Genotype
MGI:3696088

hm1

• Allelic Composition: Or8a1^tm29Mom/Or8a1^tm29Mom
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal olfactory sensory neuron morphology ( J:115911 )

• fewer cells expressing the mutant allele are present compared to control mice expressing Olfr151 promotor driven LacZ transgene

abnormal olfactory bulb morphology ( J:115911 )

• olfactory sensory neuron axons form ectopic, ventral glomeruli in the olfactory bulb in addition to glomeruli in the expected position

• two pairs of glomeruli are present in 44% of bulbs

• presence of extra glomeruli correlates to presence of 12-fold fewer cells in dorsal regions and 4- to 10-fold more cells in theventral region of the epithelium of endoturbinates II and III

craniofacial

abnormal olfactory sensory neuron morphology ( J:115911 )

• fewer cells expressing the mutant allele are present compared to control mice expressing Olfr151 promotor driven LacZ transgene

respiratory system

abnormal olfactory sensory neuron morphology ( J:115911 )

• fewer cells expressing the mutant allele are present compared to control mice expressing Olfr151 promotor driven LacZ transgene

taste/olfaction

abnormal olfactory sensory neuron morphology ( J:115911 )

• fewer cells expressing the mutant allele are present compared to control mice expressing Olfr151 promotor driven LacZ transgene

growth/size/body

abnormal olfactory sensory neuron morphology ( J:115911 )

• fewer cells expressing the mutant allele are present compared to control mice expressing Olfr151 promotor driven LacZ transgene