Or8a1^tm29Mom
Targeted Allele Detail

Summary

• Symbol: Or8a1^tm29Mom
• Name: olfactory receptor family 8 subfamily A member 1; targeted mutation 29, Peter Mombaerts
• MGI ID: MGI:3693508
• Synonyms: M71(Hom+O/E)-lacZ, M71 prom Home+O/E-IRES-taulacZ
• Gene: Or8a1 Location: Chr9:37641273-37642357 bp, - strand Genetic Position: Chr9, 20.8 cM
• Alliance: Or8a1^tm29Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:115911
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Reporter)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: Five nucleotide substitutions were made in the promoter, altering both the homeodomain and the O/E-like binding site, and an IRES-taulacZ-ACNf cassette was inserted immediately following the endogenous stop codon. The ACNf cassette self-excised in the male germline leaving no neo sequence. (J:115911)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Or8a1 Mutation: 69 strains or lines available

References

• Original: J:115911 Rothman A, et al., The promoter of the mouse odorant receptor gene M71. Mol Cell Neurosci. 2005 Mar;28(3):535-46
• All: 1 reference(s)