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Phenotypes Associated with This Genotype
Genotype
MGI:3655827
Allelic
Composition		 Foxc1tm1Blh/Foxc1+
Genetic
Background		 B6.Cg-Foxc1tm1Blh
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxc1tm1Blh mutation (0 available); any Foxc1 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal aqueous drainage system morphology ( J:82280 )
• pigmented mice had mild developmental defects than compared to albino Tyrc-2J/Tyrc-2J, Foxc1tm1Blh /Foxc1+ mice
hypoplastic trabecular meshwork ( J:82280 )
• mild hypoplasia

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
buphthalmos DOID:11211 OMIM:231300
 J:82280

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory