Phenotypes Associated with This Genotype

Genotype
MGI:3624719

• Allelic Composition: Mecp2^tm1Bird/Y; Tg(Nes-cre)1Kln/0
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:67910 )

♂

behavior/neurological

limb grasping ( J:67910 )

♂

abnormal gait ( J:67910 )

♂ • develop a stiff, uncoordinated gait

decreased locomotor activity ( J:67910 )

♂

craniofacial

abnormal tooth morphology ( J:67910 )

♂ • frequently exhibit uneven wearing of the teeth

endocrine/exocrine glands

cryptorchism ( J:67910 )

♂

growth/size/body

abnormal tooth morphology ( J:67910 )

♂ • frequently exhibit uneven wearing of the teeth

decreased body weight ( J:67910 )

♂

reproductive system

cryptorchism ( J:67910 )

♂

skeleton

abnormal tooth morphology ( J:67910 )

♂ • frequently exhibit uneven wearing of the teeth

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Rett syndrome		DOID:1206	OMIM:312750 OMIM:613454	J:67910