Analysis Tools
immune system
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• anti-CD3 antibody stimulated double positive T cell apoptosis is reduced in the thymus; however T and B cell development and B cell activation are normal
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• anti-CD3 antibody stimulated double positive T cell apoptosis is reduced in the thymus; however T and B cell development and B cell activation are normal
• after 36 hours of culture with anti-CD3 antibody homozygous T cells produce very little IL2, IL4 or IFNG unlike wild-type cells
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• reduced proliferation of splenic T cells after stimulation with anti-CD3 antibody with or without anti-CD28 antibody, especially at lower concentrations of antibodies
• however, the addition of IL2 to the culture medium increases T cell proliferation to a level similar to that of wild-type cells
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hematopoietic system
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• anti-CD3 antibody stimulated double positive T cell apoptosis is reduced in the thymus; however T and B cell development and B cell activation are normal
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• anti-CD3 antibody stimulated double positive T cell apoptosis is reduced in the thymus; however T and B cell development and B cell activation are normal
• after 36 hours of culture with anti-CD3 antibody homozygous T cells produce very little IL2, IL4 or IFNG unlike wild-type cells
|
|
• reduced proliferation of splenic T cells after stimulation with anti-CD3 antibody with or without anti-CD28 antibody, especially at lower concentrations of antibodies
• however, the addition of IL2 to the culture medium increases T cell proliferation to a level similar to that of wild-type cells
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cellular
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• anti-CD3 antibody stimulated double positive T cell apoptosis is reduced in the thymus; however T and B cell development and B cell activation are normal
|
|
• reduced proliferation of splenic T cells after stimulation with anti-CD3 antibody with or without anti-CD28 antibody, especially at lower concentrations of antibodies
• however, the addition of IL2 to the culture medium increases T cell proliferation to a level similar to that of wild-type cells
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