Phenotypes Associated with This Genotype

Genotype
MGI:3603147

• Allelic Composition: Crygb^Clapper/Crygb^Clapper
• Genetic Background: C57BL/6J-Crygb^Clapper

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Cataracts in Crygb^Clapper/Crygb^Clapper and Crygb^Clapper/Crygb⁺ mice

vision/eye

lamellar cataract ( J:100851 )

• develop dominant lamellar cataracts with lens opacity decreasing as mice age

• cataract in 3 week old homozygotes occupies the inner region and covers about 75% of the lens

• darkly stained aggregates, enlarged interfiber spaces (about 3 times wider), and disorganized and smaller inner mature fibers are seen in region of cataract

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 39 multiple types		DOID:0110236	OMIM:615188	J:100851