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Phenotypes Associated with This Genotype
Genotype
MGI:3574618
ht7
Allelic
Composition		 Dcntm1Ioz/Dcn+
Genetic
Background		 either: C.Cg-Dcntm1Ioz or C3.Cg-Dcntm1Ioz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dcntm1Ioz mutation (0 available); any Dcn mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to bacterial infection ( J:68640 )
• heterozygotes exhibit a decreased susceptibility to experimental Lyme disease, displaying a reduced arthritis incidence and severity and an intermediate number of Borrelia-positive joints (72%) relative to wild-type (90%) and homozygous mutant mice (47%)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory