Phenotypes Associated with This Genotype

Genotype
MGI:3528982

• Allelic Composition: Notch3^tm1Ul/Notch3⁺
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:95927 )

N • vascular smooth muscle is normal in the thoracic aorta and common carotid arteries and electron microscopic examination detected no abnormalities in the thoracic and abdominal aortas or the carotid, leptomeningeal, and cerebral cortical penetrating arteries

normal phenotype

no abnormal phenotype detected ( J:95927 )

• heterozygotes are viable with normal growth, reproduction, behavior, and morphology of the brain, heart, lung, eye, and skin

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	CADASIL 1	DOID:0111035	OMIM:125310	J:95927