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Phenotypes Associated with This Genotype
Genotype
MGI:3521856
Allelic
Composition
Prop1df/Prop1df
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prop1df mutation (2 available); any Prop1 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• a fraction of pups with a higher contribution of the C57BL/6J background display lethargy and die precipitously between weaning and adulthood

endocrine/exocrine glands
N
• mutants crossed onto the C57BL/6J background have normal levels of gonadotropes

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
hypopituitarism DOID:9406 OMIM:221750
OMIM:262600
OMIM:262700
OMIM:613038
OMIM:613986
J:94409


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory