Phenotypes Associated with This Genotype

Genotype
MGI:2661058

• Allelic Composition: Gusb^tm4Sly/Gusb^tm4Sly
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:83169 )

• incomplete penetrance

craniofacial

abnormal neurocranium morphology ( J:83169 )

• sclerosis of the calvarium

shortened head ( J:83169 )

• progressive with age

growth/size/body

shortened head ( J:83169 )

• progressive with age

decreased body size ( J:83169 )

postnatal growth retardation ( J:83169 )

• progressive with age

hearing/vestibular/ear

deafness ( J:83169 )

limbs/digits/tail

short limbs ( J:83169 )

• progressive with age

skeleton

abnormal axial skeleton morphology ( J:83169 )

• dysplasia

abnormal neurocranium morphology ( J:83169 )

• sclerosis of the calvarium

osteosclerosis ( J:83169 )

• sclerotic long bones

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
mucopolysaccharidosis type VII		DOID:12803	OMIM:253220	J:83169