Phenotypes Associated with This Genotype

Genotype
MGI:2655680

• Allelic Composition: Myc^tm1Atp/Myc^tm1Atp
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal chorion morphology ( J:137630 )

• fetal blood vessels and allantoic mesenchyme fail to invade the chorion compartment unlike in wild-type mice

abnormal placenta morphology ( J:137630 )

• mice exhibit abnormal chorioallantoic placenta with a failure of branching morphogenesis

• fewer proliferating cells are found within the placenta compared to in wild-type mice

placental labyrinth hypoplasia ( J:137630 )

abnormal trophoblast layer morphology ( J:137630 )

• the number of epithelial derived choronic-trophoblast cells is decreased compared to in wild-type mice

cardiovascular system

cardiovascular system phenotype ( J:137630 )

N • embryonic vasculature development is normal