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Phenotypes Associated with This Genotype
Genotype
MGI:2651448
Allelic
Composition		 Pax8tm1(cre)Mbu/Pax8tm1(cre)Mbu
Genetic
Background		 involves: 129P2/OlaHsd * C3H/He * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax8tm1(cre)Mbu mutation (0 available); any Pax8 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality at weaning, complete penetrance ( J:80208 )
• animals died at weaning age

endocrine/exocrine glands

growth/size/body
postnatal growth retardation ( J:80208 )

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
congenital hypothyroidism DOID:0050328 OMIM:PS275200
 J:80208

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory