Phenotypes Associated with This Genotype

Genotype
MGI:2179092

• Allelic Composition: Socs2^hg/Socs2^hg
• Genetic Background: involves: AKR/J * C3H/HeJ * C57BL/6J * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

abnormal body weight ( J:7780 )

• weaning weight is slightlky lower than expected

• weight gain between 21 and 42 days of age is 30-50% higher in mutant mice compared with wild-type

• weight at maturity remains higher than recorded for wild-type

increased body weight ( J:7780 )

• weight gain between 21 and 42 days of age is 30-50% higher in mutant mice compared with wild-type

reproductive system

abnormal fertility/fecundity ( J:7780 )

• Background Sensitivity: fertility in both sexes may be normal or as much as 40 per cent lower than recorded for wild-type mice

• Background Sensitivity: 100% of mutant mice are fertile when the genetic background is 96.9% at N5

homeostasis/metabolism

abnormal energy expenditure ( J:8237 )

decreased energy expenditure ( J:8237 )

• Background Sensitivity: the maintenance energy requirement in mutant mice is decreased compared with the requirement of wild-type mice

• Background Sensitivity: efficiency of growth of mutant mice is increased compared with wild-type mice