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Phenotypes Associated with This Genotype
Genotype
MGI:2175798
Allelic
Composition
Cryaalop18/Cryaalop18
Genetic
Background
involves: CBA/CaGnLeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cryaalop18 mutation (1 available); any Cryaa mutation (14 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• degeneration of lens cortex
• posterior migration of lens epithelial nuclei
• vacuoles in lens noted at E14; prominent by E16
• abnormal fibers form at posterior pole of lens
• apparent at weaning age; progressive severity with age

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
cataract 9 multiple types DOID:0110266 OMIM:604219
J:34933


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory