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Phenotypes Associated with This Genotype
Genotype
MGI:2173453
Allelic
Composition		 Chrdtm1Emdr/Chrdtm1Emdr
Nogtm1Amc/Nogtm1Amc
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chrdtm1Emdr mutation (1 available); any Chrd mutation (50 available)
Nogtm1Amc mutation (3 available); any Nog mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal direction of heart looping ( J:137629 )
• at E9.0 mutants show no directional looping of the heart; cardiac looping is abnormal or reversed in >90% of embryos

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory