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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Casp1em1Stewi
endonuclease-mediated mutation 1, Stefan Winkler
MGI:8433190
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Casp1em1Stewi/Casp1em1Stewi involves: C57BL/6NCrl MGI:8433201


Genotype
MGI:8433201
hm1
Allelic
Composition		 Casp1em1Stewi/Casp1em1Stewi
Genetic
Background		 involves: C57BL/6NCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Casp1em1Stewi mutation (0 available); any Casp1 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
decreased cell death ( J:288227 )
• after intraperitoneal injection of low dose of LPS

digestive/alimentary system
peritoneal inflammation ( J:288227 )
• stronger influx of neutrophils and monocytes after intraperitoneal injection of low dose of LPS

immune system
peritoneal inflammation ( J:288227 )
• stronger influx of neutrophils and monocytes after intraperitoneal injection of low dose of LPS




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory