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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Eya3em1Rsheg
endonuclease-mediated mutation 1, Rashmi S Hegde
MGI:8403171
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Eya3em1Rsheg/Eya3em1Rsheg C57BL/6J-Eya3em1Rsheg MGI:8403192


Genotype
MGI:8403192
hm1
Allelic
Composition
Eya3em1Rsheg/Eya3em1Rsheg
Genetic
Background
C57BL/6J-Eya3em1Rsheg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eya3em1Rsheg mutation (0 available); any Eya3 mutation (398 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• no muscularization of pulmonary arterioles after return to normal air after 3 weeks in hypoxic conditions
• reduced RV-weight-to-LV+septum-weight ratio after return to normal air after 3 weeks in hypoxic conditions owing to reduced RV hypertrophy
• lower RVSP after return to normal air after 3 weeks in hypoxic conditions
• normal RVSP in normal air

embryo
N
• viable

mortality/aging
N
• viable

reproductive system

respiratory system
N
• normal lung morphology





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/14/2026
MGI 6.24
The Jackson Laboratory